Resun Nanocoulter Technology is Used for the Analysis of Small Particles in Standard Nanoscale Microspheres

—Analyze the content of small particles in standard microspheres produced by different manufacturers

Nanospheres have various usages. Different applications require different properties of microspheres. Many high-end applications have high requirements for particle size and uniformity of nanospheres. In the application of microspheres, we generally judge the size of nanospheres by the given nominal size, and the particles outside the nominal size must have an impact on some specific applications. Resun’s Nanocoulter technology can analyze the content of small particles in the corresponding nomi.

The following is the small particle signal analysis of Resun Nanocoulter test standard spheres from two manufacturers:

1) The embodiment of small particles in the pulse diagram:

2) According to the corresponding relationship between particle size and peak value, the content of particles with nominal particle size below 67% in standard microspheres with nominal particle size of 150nm, 200nm and 300nm from two manufacturers (manufacturer B and manufacturer G are used here) is analyzed:

3) According to the test of microspheres with nominal particle sizes of 150nm, 200nm and 300nm from different manufacturers, the CV values of each particle size are statistically analyzed as follows:

As shown in the two figures above:

1) In 150nm and 300nm nanospheres, the content of small particles of manufacturer B is higher than that of manufacturer G, and the content of small particles of manufacturer G in 200nm nanospheres is higher than that of manufacturer B;

2) In the CV value of tested particle size, the CV of 200nm microsphere of manufacturer B is smaller than that of manufacturer G.

3) Compared with electron microscope data;

The following is the SEM diagram of the 300nm nominal particle size microsphere of manufacturer B, from which it can be clearly seen that there are small particles.